Keynote speaker

“Robin Weiss, London and Hendrik Streeck, Germany”

"Christine Leib-Mösch, Germany"


- Monday 24 August

17:00 - 17:45

Registration/ Light refreshments

17:45 - 18:00

Meeting Address: Ulf Dittmer an Susan Ross

18:00 - 18:40
Keynote Lecture, Hendrik Streeck, University of Duisburg-Essen; “Multi-layered, multifaceted role of CD4 T cell immune responses in HIV infection”

18:40 – 20:15
Session I
Entry and Early Events

Chair: Stocking

18:40 – 19:00
Leslie Parent; University of Toronto; ” Evidence that initial Gag-RNA interactions occur in the nucleus”

19:00 – 19:20
Jiri Hejnar, Institute of Molecular Genetics, Prague; „Genetic diversity of NHE1, receptor for subgroup J avian leukosis virus, in domestic and wild bird species“

19:20 – 19:40
Carlos de Noronha, Albany Medical College; “Sulforaphane inhibits HIV infection of macrophages through Nrf2”

19:40 – 20:00
Dirk Lindemann, Technical University of Dresden; ”Prototype Foamy Virus Gag interaction with host cell polo-like kinases is important for efficient virus entry”

20:00 – 20:15
Xaver Sewald, Yale University; “Retrovirus spread in vivo depends on CD169/Siglec-1 mediated trans-infection of permissive lymphocytes”

- Tuesday 25 August

08:00 – 09:00

09:00 – 13:35 Session II
Replication Chair: Stoye

09:00 – 09:20
Karen Beemon, Johns Hopkins University Baltimore; “PTBP1 Protects Retroviral and Cellular mRNA from Nonsense-mediated mRNA Decay (NMD)”
09:20 – 09:40
Leonard Evans, Rocky Mountain Laboratories, Hamilton; “Profound Elevation of Polytropic MuLV Infectivity After Superinfection with an Ecotropic MuLV”
09:40 – 10:00
Monica Roth, Rutgers-RW JMS Pharmacology; “Murine Leukemia Virus Integration: Structural studies of IN for Viral and Target Recognition”

10:00 – 10:30
Coffee Break

10:30 – 10:50
Marie-Louise Hammarskjöld, University of Virginia; “HIV, antisense RNA and ADAR editing”
10:50 – 11:10
Stanislav Indik, University of Veterinary Medicine Vienna; “Steady state between the rate of DNA polymerization and the rate of RNA degradation during reverse transcription determines the sensitivity of MMTV to APOBEC3 proteins”
11:10 – 11:30
David Rekosh, University of Virginia; HIV Rev/RRE sequence variation modulates viral replication by promoting the assembly of complexes with different levels of functional activity”
11:30 – 11:50
Susan Ross, University of Pennsylvania; “Identification of cytosolic sensors that recognize retroviral and retroelement cytosolic DNA”

11:50 – 13:00

13:00 – 13:20
Birgitta Wöhrl, University of Bayreuth; “Biochemical characterization of a multiresistant subtype AG reverse transcriptase: AZT resistance and sensitivity to RNase H inhibitors”
13:20 – 13:35
Lieve Dirix, KU Leuven; “A single-virus study of HIV-1 nuclear import”
13:35 – 14:15
Keynote Lecture: Robin Weiss, University College London; “How IIamas help HIV research”
14:15 – 16:15
Poster Session
17:30 – 19:00
Guided Tour: "About Coal and Miners", Meeting Point RUHR.VISITORCENTER Essen/Besucherzentrum Ruhr, Areal A, Gelsenkirchener Str. 181, 45309 Essen

Dinner – Restaurant & Café “Die Kokerei”


- Wednesday 26 August

08:00- 09:00

9:00 – 13:20 Session III Restriction Factors
Chair: Neil

09:00 – 09:20
Mario Santiago, University of Colorado Denver; “IFN alpha subtypes in an ex vivo model of acute HIV-1 infection: expression, potency and effector mechanisms”
09:20 – 09:40
Hung Fan, University of California, Irvine; “Human and Murine APOBEC3s Restrict Replication of Koala Retrovirus by Different Mechanisms”
09:40 – 10:00
Jonathan Stoye, MRC/NIMR Virology London; “Evolution of restriction specificity in Fv1”

10:00 – 10:30
Coffee Break

10:30 – 10:50
Valgerdur Andresdottir, University of Iceland; „The Vif protein of maedi-visna virus“
10:50 – 11:10
Ulrike Sauermann, Deutsches Primatenzentrum Göttingen; “FAM26F expression levels in PBMCs before SIV infection inform about overall plasma viral load in the acute and postacute phase of infection”
11:10 – 11:30
Jaquelin Dudley, University of Texas at Austin; “Rem as a Protein Antagonist of Apobec family members”
11:30 – 11:50
Christine Kozak, National Institute of Allergy and Infectious Diseases; “Analysis of mouse leukemia viruses from geographically separated Mus taxa identify adaptive mutations at sites that interact with 4 host restriction factors”

11:50 – 13:00

13:00 – 13:20
Richard Sloan, Queen Mary University of London; “IFITM proteins restrict HIV protein synthesis”
13:20 – 14:00
Keynote Lecture: Christine Leib-Mösch, Helmholtzzentrum Munich; ”Endogenous retroviruses in the human genome: Do parasites control our genes?”

14:00 – 17:00 Session IV Immune responses
Chair: Dudley

14:00 – 14:20
Scott Kittchen, David Geffen School of Medicine at UCLA; “Characterization of immune exhaustion and type I IFN signaling during chronic HIV infection in humanized Bonemarrow/Liver/Thymus (BLT) mice”
14:20 – 14:50
Torben Knuschke, University of Duisburg-Essen; ”A nanocarrier-based approach to enhance anti- retroviral immunotherapy by reactivation of virus-specific T cell”
14:50 – 15:10
Mireia Pelegrin, Institute of Molecular Genetics of Montpellier; ”Antiviral monoclonal antibodies induce long-lasting antiviral immunity through FcgR-binding effector functions”

15:10 – 15:40
Coffee break

15:40 – 16:00
Kim Hasenkrug; Rocky Mountain Laboratories, Hamilton; - Cancelled -
16:00 – 16:20
Ulf Dittmer; University of Duisburg-Essen; “Regulatory T cells and inhibitory receptors suppress cytotoxic T cell and NK cell responses in retroviral infections”
16:20 – 16:40
William Green, Geisel School of Medicine at Dartmouth, Lebanon; “Monocytic myeloid derived suppressor cells following LP-BM5 retrovirus infection: M-MDSC subsets and differential suppressive mechanisms, targeted cells, and regulation”
16:40 – 17:00
Wibke Bayer, University of Duisburg Essen; "Advancement of adenovirus-based immunization strategies in the Friend retrovirus model"

Dinner - Wolfsburg


- Thursday 27 August

08:00 – 09:00

9:00 – 11:20
Session V Oncogenesis, Pathogenesis
Chair: Beemon
09:00 – 09:20
James C. Neil, University of Glasgow; “Intrinsic barriers to zoonotic infection by feline leukemia viruses are frequently lost in malignant cells”
09:20 – 09:50
Karin Peterson, Rocky Mountain Laboratories, Hamilton; “Neuropeptide Y negatively regulates monocyte/macrophage recruitment to the CNS during retrovirus infection”
09:50 – 10:10
Paul Jolicoeur, University of Montreal; ”Pathogenesis of HIV-induced kidney Disease”

10:10 – 10:40
Coffee Break

10:40 – 11:00
Mary Poss, Penn State University; “Is there a retroviral etiology of large granular leukocyte leukemia?”
11:00 – 11:20
Christiane Stahl-Henning, Deustches Primatenzentrum,Göttingen; ”Attenuated phenotype of a SIV vpr deletion mutant in macaques”

11:45 – 13:00

13:00 – 14:10
Session VI New viruses and Endogenous retroviruses
Chair: Ross
13:00 – 13:20
Martin Löchelt, German Cancer Research Center (DKFZ), Heidelberg; “In Vitro Evolution of High Titer Bovine Foamy Virus: Identification and Functional Characterization of Key Mutations”
13:20 – 13:50
Sandra Quakenbush, Colorado State University; “Transmission of Bighorn Sheep Sinus tumors and Identification of Retroviral Sequences”
13:50 – 14:10
Venkat Yedavalli, National Institut of Allergy and Infectious Diseases, Bethesda; “Sequence and functional characterization of a unique full-length endogenous retrovirus in the spumaretroviral ERV-L family found in Xenopus tropicalis
End of the meeting


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